Zubrus notched the go-ahead goal late in the second period when he one-timed a pass from Adam Henrique past Ilya Bryzgalov from in close, and later made it 4-2 with an empty-netter.
Petr Sykora and Marek Zidlicky each added a goal and an assist as the Devils charged back from an early 2-0 deficit to log the victory and put the Flyers on the brink of elimination in their conference semifinal series.
Veteran New Jersey goalie Martin Brodeur celebrated his 40th birthday with a win, stopping 20-of-22 shots for the Devils.
Bryzgalov finished with 39 saves.
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