Bynum's defensive feat matched the record for most shots blocked in an NBA post-season contest, equaling a mark set previously by Hakeem Olajuwon and Mark Eaton.
The center also netted 10 points to go with 13 rebounds to register the first Lakers post-season triple-double since Magic Johnson's performance in the 1991 NBA Finals against the Chicago Bulls.
Kobe Bryant went 11-of-24 from the floor on his way to 31 points as the Lakers grabbed a 1-0 lead in their Western Conference quarterfinals series against the Nuggets.
Denver was paced by Danilo Gallinari with 19 points.
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