Rose scored 23 points to go with nine rebounds and nine assists in the Bulls' 103-91 playoff-opening win over Philadelphia Saturday.
But he had to be helped off the court with 1:10 left in the game after jump-stopping in the lane while throwing a pass. Rose crumpled to the floor and grabbed his left knee before being taken to the locker room.
He was later diagnosed with a torn anterior cruciate ligament.
"It's part of the game. There are going to be injuries," Bulls Coach Tom Thibodeau said. "A guy could get hurt in practice, a guy could get hurt in the first 5 minutes of the game. He can get hurt at the end of the game. He can get hurt any time, and you've got to deal with it."
Notable deaths of 2014 [PHOTOS]