The playoff-bound Pacers won their fourth straight and stayed three games ahead of fourth-seeded Boston in the Eastern Conference.
They got 21 points and seven rebounds from Danny Granger in the victory.
Milwaukee's playoff hopes, meanwhile, took a hit despite 20 points from Monta Ellis.
With the loss, the Bucks dropped 2 1/2 games behind New York and Philadelphia in the race for the final playoff spots in the East.
Brandon Jennings added 16 points, 10 assists and eight rebounds in Milwaukee's setback.
Notable deaths of 2014 [PHOTOS]