Wilson (2-0) held the Yankees to one run on six hits over six frames, walking two and striking out two en route to the victory, his second in two starts since agreeing to five-year, $77.5 million deal with Los Angeles in December.
Yankees starter Phil Hughes (0-2) was raked for six runs on eight hits over 3 1/3 innings.
Robinson Cano drove in New York's only run.
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