Oklahoma City has lost three in a row for the first time this season. The Thunder had dropped back-to-back outings only one other time, those setbacks coming in the sixth and seventh games of the season.
Granger finished with 24 points and was a key to the Pacers opening a 12-point lead after the first quarter. Indiana led by as many as 20 in the third period, but the Thunder closed within three with 6 seconds to play on a 3-pointer by Russell Westbrook.
Granger then hit two free throws to finally put the game away. Roy Hibbert added 21 for Indiana, which won its fourth in a row.
The Thunder fell despite a big game from Kevin Durant, who scored 44 points. Westbrook tallied 21 points with 11 rebounds and nine assists.