Granger scored 20 points in the Pacers' third victory over Washington in as many weeks. Those were the only three games scheduled between the teams this season.
Darren Collision contributed 17 points and 11 assists for the Pacers, winners of three in a row. Indiana turned a one-point halftime lead into a 12-point cushion heading into the fourth quarter.
Jordan Crawford led Washington with 28 points, 21 during the first half. Kevin Seraphin scored a career-best 19 points to go with 10 rebounds.
Washington lost its third straight and has dropped 10 of 12. The Wizards' 12 victories this season are second-fewest in the NBA.