Granger went 3-of-5 from 3-point territory while Paul George had 16 points and 10 rebounds for the Pacers, who won for the fourth time in five games. David West had 10 points and 12 boards as the Pacers broke a five-game skid against Miami.
Dwyane Wade knocked down four from long range en route to 24 points and LeBron James also scored 24 for the Heat, who lost for the second time in two nights.
Chris Bosh scored 14 points but was limited to only two rebounds for Miami.
Notable deaths of 2014 [PHOTOS]
Michael Sam cut from the Dallas Cowboys