Isaiah Thomas drained four 3-pointers en route to 18 points, John Salmons added 15, and Jason Thompson produced a double-double of 13 and 10 rebounds for the Kings, who improved to 4-3 on the long homestand.
Sacramento led by as many as 20 points with the help of a combined 23 bench points from Donte Green and Charles Hayes.
The Timberwolves, meanwhile, got 21 points and 11 rebounds from Kevin Love.
The all-star forward got into a heated argument with teammate J.J. Barea during a late timeout and had to be separated from him.
The loss was the fifth in six contests for the T-Wolves, who fell two games below .500 for the season.