Manassero had nine birdies and a bogey in an 8-under-par 64 at the Aloha Golf Club.
Five players are tied for second at 5-under. That includes Niclas Fasth, who had three bogeys including one on his final hole Thursday, and Anthony Wall, had eight birdies against a bogey and a double bogey.
Also at 5-under are Eduardo de la Riva, who had one bogey, Otto Hennie, after a bogey-free round, and Lloyd Kennedy, whose round included an eagle and a bogey.
Manassero played the back side at Aloha first and opened with a birdie. After four consecutive pars he closed the side with three birdies in a four-hole span.
He had three more birdies over Nos. 3-6 but had a bogey at the seventh hole.
Manassero dropped an 18-foot putt for birdie at the eighth hole and pitched to within 7 feet for a birdie opportunity at the 343-yard ninth hole to tie the record.
Swim Week Miami Beach 2014 [PHOTOS]