The fourth-seeded Del Potro, who also reached the finals in last week's ATP Tour tournament in Rotterdam, dispatched the Frenchman 6-4, 6-4, capturing his first title of 2012.
The Argentine won won 36-of-40 first-serve points against Llodra and didn't face a single break point against his own serve en route to the victory, which was a rematch from the first round of the Rotterdam event.
Del Potro fell to Roger Federer in the Netherlands finals.
Del Potro improved to 10-5 in career finals while Llodra slipped to a 5-5.
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