Both were hurt Saturday during the Spurs' overtime victory over the Los Angeles Clippers.
Magnetic resonance imaging confirmed Ginobili sustained a left internal oblique strain. The 10-year veteran, who has played in nine games this season due to a broken left hand, is averaging 12.1 points, 3.3 assists and 2.9 rebounds.
Splitter strained his right calf. The reserve forward is averaging 9.4 points and 5.2 rebounds in 31 games.
San Antonio is on a 10-game win streak.