Charlotte equaled the longest losing streak in franchise history and will seek to avoid setting a club record when it hosts the Los Angeles Clippers Saturday.
Chicago shot only 43 percent from the field but grabbed 18 offensive rebounds and forced 16 turnovers.
Noah scored 17 points and claimed 14 boards, sending the Bulls to their fifth consecutive triumph. Chicago is 6-2 on a nine-game road trip.
Carlos Boozer added 16 points. The lopsided win came without Derrick Rose in uniform. The defending league MVP rested his sore back.
Derrick Brown was the only Charlotte player in double figures with 10 points.