Howard scored 19 points, had 16 rebounds and blocked eight shots as part of Orlando's second straight win. The back-to-back victories have come after a four-game slide.
Howard went into the contest leading the NBA with 15.4 rebounds per game. He made only 5-of-12 shots from the field, but dominated in the paint while Orlando was building a 19-point lead heading into the fourth quarter.
Cleveland, which has lost three out of four, got 20 points from Alonzo Gee.
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