The Miami Dolphins receiver set a Pro Bowl record with the scoring grabs of 74, 29, 47 and 3 yards, finishing with six catches for 176 yards.
His third touchdown -- a 47-yard catch-and-run from Cincinnati's Dalton -- early in the third quarter put the AFC ahead for good at 38-35.
Carolina rookie Cam Newton also threw two TDs but was picked off twice by San Diego's Eric Weddle.
Larry Fitzgerald of Arizona caught six passes for 111 yards and three touchdowns in the NFC's loss.
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