Rose dished off eight assists and grabbed five rebounds for Chicago after missing four games with a left big toe sprain.
Joakim Noah also returned to action Monday after missing the Bulls' previous game with an ankle sprain, providing 16 points and 10 rebounds in the win.
Richard Hamilton had 22 points -- including his 15,000th career point -- and 10 assists.
The Eastern Conference-leading Bulls ran their record to a league-best 16-3 and remained undefeated at home (8-0).
NBC reportedly holds celebs hostage to Jimmy Fallon's show
Ray Liotta sues skin care company over use of likeness