After Detroit dominated most of the 4-of-4 extra frame, Valtteri Filppula launched a shot from the left circle that bounced high off the shoulder of Blackhawks netminder Corey Crawford.
It ricocheted straight to Bertuzzi in the slot, who knocked it into the net out of midair and secured the Red Wings' team record-tying 14th consecutive home win.
Bertuzzi's first goal came on a breakaway in the first period.
Andrew Shaw also found the net and Crawford finished with 40 saves for the Blackhawks.
Notable deaths of 2014 [PHOTOS]
UPI Sports Results for September 19, 2014