The 76ers played at home for the first time this season after opening the campaign with a 3-2 road trip. They won their third straight.
Philadelphia held a seven-point lead heading into the fourth quarter, and then turned the game into a runaway with a 32-point period. The Pistons scored just three points over the final 5:45.
Detroit was held to 36 percent shooting from the field and missed all 10 of its 3-point tries. Greg Monroe led the Pistons with 22 points.
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