The Senators won their third in a row and handed the Southeast Division-leading Panthers their second straight setback.
Ottawa never trailed, but each time the Senators scored during regulation the Panthers were able to answer.
It was a 1-1 game heading into a wild third period, which got going when Ottawa's Daniel Alfredsson scored for Ottawa on the power play. Shawn Matthias tied it less than 2 minutes later.
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