Vick has missed two games since suffering two broken ribs in a game against Arizona. Vince Young has started the games in Vick's place at quarterback. The Eagles, who are 4-7 overall, are 1-1 in those games.
Young has passed for 658 yards the last two weeks, including 400 in a loss Sunday to New England. Young is expected to get the start in quarterback against Seattle.
The Eagles also said wide receiver Jeremy Maclin, who has hamstring and shoulder injuries; cornerback Dominique-Cromartie, who has an injured ankle; and linebacker Moise Fokou, who also has an ankle problem, have also been ruled out for Thursday's game.