Trailing 1-0 for most of the game, Minnesota pulled its goalie to add an extra attacker as time wound down. Justin Falk unleashed a wrist shot from the point that Mikko Koivu deftly deflected into the net for the equalizer with 1 minute left.
Koivu leveled Red Wings defenseman Niklas Kronwall with a shoulder check and fed the puck to Setoguchi at the crease, who knocked in the rebound of own shot for the game-winner.
Harding stopped 36-of-37 shots and logged his second win in three days over Detroit, which was swept in a home-and-home series with Minnesota.
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