One batter later, Hairston broke for home and Lucroy laid down a perfect bunt to the right of Ziegler, who threw wildly to home.
That opened the doors to four more runs as the Brewers collected consecutive run-scoring hits from Corey Hart, Nyger Morgan and Ryan Braun (3-for-4, three RBI), grabbing a commanding 2-0 lead in their best-of-five NL Division Series against the Diamondbacks.
Braun cracked a two-run homer and Takashi Saito (1-0) earned the victory for Milwaukee.
Hudson yielded five runs on nine hits over 5 1/3 innings and Justin Upton clubbed a two-run homer for the Diamondbacks, who will look to avoid a sweep when they host Game 3 Tuesday in Phoenix.
Notable deaths of 2014 [PHOTOS]