Lee hit a tap toward third and Reimold beat a high throw home and broke a 2-2 tie.
Jon Rauch (2-3) came in for Frasor and, after a walk loaded the bases, Adams singled to left and Felix Pie, who ran for Scott, scored.
Jason Berken (1-2) had two innings of no-hit relief, striking out two to get the victory. Kevin Gregg, who allowed a home run to Adam Lind -- his 14th -- leading off the ninth, still collected his 13th save.
J.J. Hardy broke a scoreless tie by leading off the sixth with his seventh home run of the year and the Orioles added a run with an RBI double from Guerrero.
Baltimore starter Jeremy Guthrie had a one-hitter through five innings but was lifted for reliever Jim Johnson.
Toronto's Jayson Nix greeted Johnson with a single in the bottom of the inning. After Yunel Escobar reached on an error and the runners were advanced with a sacrifice, Jose Bautista delivered a two-run single to center.