The Red Storm played as a ranked team for the first time in 11 years.
Hardy scored 21 points and Paris Horne added 14 for St. John's (18-9, 10-5 Big East Conference). A 12-point run by the Red Storm opened a 19-point cushion with 3 minutes to go in the first half and the Blue Demons could not make a game of it after that.
St. John's also got 11 points and 10 rebounds from D.J. Kennedy while winning its fifth in a row.
Cleveland Melvin led DePaul (7-20, 1-14) with 16 points. After winning their only league game against Providence, the Blue Demons have dropped two straight.