Dixon connected on a trio of 3-pointers and Ricardo Ratliffe added 13 points for the Tigers (19-6, 5-5 Big 12), who improved to 15-0 on their home court.
Justin Safford chipped in with 11 points and Laurence Bowers pulled down nine rebounds to go with eight points as Missouri bounced back from a loss at Kansas earlier in the week.
Cameron Clark led the Sooners (12-12, 4-6) with 16 points and Tyler Neal added 14 in the setback.
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