Alex Oriakhi popped in 15 points and grabbed 16 rebounds for the Huskies (4-0), who moved on to Wednesday's championship game in a surprise result.
Roscoe Smith chipped in with eight points and eight rebounds for UConn, which earned some payback for a loss to Michigan State in the semifinals of the 2009 NCAA Tournament.
The Spartans (3-1) got 22 points and 12 rebounds from Draymond Green and Durrell Summers contributed 13 points in the setback.
Michigan State's record in Maui Invitational semifinal games fell to 1-2 with the loss.
Justin Bieber crashes Drake Bell's album release party
Chipotle plans first price increase in 3 years