A bruised shoulder didn't seem to slow down Mallett, who found Jarius Wright on a pair of scores while completing 27-of-44 passes for the Razorbacks (6-2, 3-2 SEC).
Wright hauled down six receptions for 88 yards for Arkansas.
The Razorbacks' 556-yard ground attack was keyed by Knile Davis, who rushed for 81 yards and two touchdowns on 19 carries.
The Commodores (2-6, 1-4) were shut down offensively. Quarterback Larry Smith threw just 12 times, completing four passes for 25 yards.
Exploding whale video goes viral on Internet
Martin Bashir resigns from MSNBC over Sarah Palin comments