Greg McElroy finished the game 11-of-17 passing for 84 yards and C.J. Mosley returned an interception for a touchdown for the Crimson Tide (5-0, 2-0 SEC), who won their 29th straight regular-season game.
Florida (4-1, 2-1) was led by quarterback John Brantley, who completed 16-of-31 pass attempts for 202 yards and was picked off twice.
The Gators were plagued by four turnovers in the defeat.
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