Woods had six birdies in a bogey-free round at the Celtic Manor course in Newport.
The 22-year-old Wood has not yet won on the tour but has finished in the Top 10 in his last three events.
"I struggled a little bit with the pace of uphill putts, but I had some really good shots and gave myself quite a lot of chances," Wood said after his opening round in Wales.
"No bogeys is always pleasing," he said.
The Celtic Manor course is to be the site of the Ryder Cup in October.
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