Rajon Rondo produced a triple-double with 22 points, 10 rebounds and 13 assists for Boston.
Toronto's Chris Bosh had 31 points and 13 rebounds for his 27th double-double of the season, tops in the NBA.
Andrea Bargnani added 23 points for the Raptors.
Boston has defeated Toronto seven times in a row.
Ray Liotta sues skin care company over use of likeness
Boston schools pull out free condoms over wrapping complaints