The Pistons lost their 11th game in a row.
The Spurs had only a two-point lead to open the final period, but made 15-of-20 shots from the field during those 12 minutes and outscored the Pistons 35-17.
The losing streak is Detroit's longest since the 1993-94 season, when the Pistons dropped 13 straight.
Detroit was led by 29 points from Richard Hamilton.
Pistorius testifies he didn't consciously pull trigger when he shot girlfriend
Google buys drone maker Titan Aerospace