Radim Vrbata notched a goal and Ilya Bryzgalov recorded 25 saves for Phoenix.
The Coyotes got first-period goals from Upshall and Lombardi and used nine saves from Bryzgalov in the period to take charge of the game. Doan's goal at 4:39 of the second period virtually iced the win.
Derick Brassard and Antoine Vermette each scored for the Blue Jackets, who have dropped seven straight games.
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