The yardage, a career-high total and the fourth 200-yard receiving game in franchise history, led the Vikings to a 27-10 win over the Lions.
Rice, in his third NFL season from the South Carolina, has made nine catches of at least 25 yards this season and is the fourth Viking to be honored this season, joining quarterback Brett Favre (offense), linebacker Chad Greenway (defense) and wide receiver/kick returner Percy Harvin (special teams).
Other NFC honors went to Green Bay safety Charles Woodson (defense) and Washington punter Hunter Smith (special teams).
Woodson helped the Packers beat Dallas, 17-7, with a team-high nine tackles, an interception, two forced fumbles and one sack.
Smith, a quarterback in high school, tossed a 35-yard touchdown pass on a fake field goal, leading the Redskins to a 27-17 win over Denver.