NFL: Indianapolis 42, St. Louis 6

ST. LOUIS, Oct. 25 (UPI) -- Peyton Manning's three touchdown passes Sunday paced the unbeaten Indianapolis Colts to an easy 42-6 win over the St. Louis Rams.

Manning threw two scoring passes in the first half on the way to a 21-3 lead at the break and, in all, completed 23-of-34 passes for 235 yards.

Reggie Wayne caught seven passes for 83 yards with one touchdown.

Joseph Addai rushed for 64 yards on 20 carries with one touchdown. Jacob Lacey scored on a 35-yard, third-quarter interception return for the Colts (6-0), who stretched their regular-season winning streak to 15 straight games.

St. Louis quarterback Marc Bulger was just 14-of-26 passes for 140 yards with two costly interceptions.

Steven Jackson rushed for 134 yards on 23 carries, and Josh Brown kicked two field goals for the winless Rams (0-7), who have lost 17 straight dating back to last season.