NFL: Indianapolis 14, Jacksonville 12

INDIANAPOLIS, Sept. 13 (UPI) -- Peyton Manning passed for 301 yards and a touchdown Sunday, guiding the Indianapolis Colts to a 14-12 victory over the Jacksonville Jaguars.

Manning, completing 28-of-38 passes, hit Reggie Wayne on a 35-yard scoring play in the third quarter.

Joseph Adai ran 3 yards for another touchdown for Indianapolis (1-0) in the debut of new Coach Jim Caldwell, who was an assistant to former head Coach Tony Dungy.

Maurice Jones-Drew ran 21 times for 97 yards and scored on a 7-yard touchdown run for the Jaguars (0-1)

Jacksonville quarterback David Garrard was 14-of-28 for 122 yards.