Stricker closed with a 4-under 67 to finish at 17-under 267.
"It was tough. Even though the wind wasn't blowing (hard), there was enough of a breeze that it was swirling around a bit, and that made club selection difficult at times, and the pins were tough," said Stricker, who earned $1.35 million for the victory.
Stricker also moved past Tiger Woods for the No. 1 spot in the FedEx Cup standings. Woods shot a 63 Monday and ended in a tie for 11th at 12-under 272.
Stricker was one stroke better than Scott Verplank (67) and Jason Dufner (65), who shared second at 268. Dustin Johnson (66), Masters champion Angel Cabrera (65) and three-time major winner Padraig Harrington (68) ended in a tie for fourth at 15-under 269.