Luis Fabiano scored twice to tie the score after the U.S. team had jumped out 2-0 in the first 27 minutes.
The victory was the Brazilians' second straight Confederations Cup title, and third overall.
The United States, playing in its first FIFA final, came into the tournament unbeaten in 96 straight matches when leading at the half since 1993. The Americans reached the final in Johannesburg, South Africa, by upsetting world No. 1 Spain 2-0 in the semifinals.
Notable deaths of 2014 [PHOTOS]
UPI Sports Results for September 19, 2014