St. Louis needed a victory over the Blue Jackets and a loss by Nashville to Minnesota to earn the post-season spot and the Blues got both.
Columbus, which is sixth in the Western Conference playoff standings, came up with a goal by Jiri Novotny and 22 saves from Steve Mason.
St. Louis defeated Columbus in five of their six meetings this season.
Lytro unveils camera that can focus a photo after shooting it
Moore to attend retreat in to avoid Kutcher's wedding