The pass-rushing specialist, in his ninth NFL season out of San Diego State, had compiled 74 1/2 sacks.
Last season, he surpassed the 68 1/2 sacks made by the late Reggie White.
In 2008, he played in seven games, starting once, and was credited with eight solo tackles, but just one-half sack.
"We want to thank Kabeer for his contributions to the Green Bay Packers," General Manager Ted Thompson said on the team's Web site. "During his time here, he has been a big part of our organization and our community. We wish Kabeer and his family well."
"My nine years as a Green Bay Packer have been a blessing that is beyond words," Gbaja-Biamila said. "I thank God for bringing me to this first-class organization and first-class community."
In his place, Green Bay activated defensive tackle Justin Harrell off the physically unable to perform list.