NFL: New York Giants 29, San Francisco 17

EAST RUTHERFORD, N.J., Oct. 19 (UPI) -- Brandon Jacobs scored twice Sunday for the New York Giants, who rebounded from a loss in Cleveland with a 29-17 victory over the San Francisco 49ers.

The defending Super Bowl champion Giants (5-1) were pounded 35-14 by the Browns Monday but led all the way against San Francisco.

Jacobs had touchdown runs of 26 and 2 yards against the 49ers (2-5), who have lost four straight games.

Eli Manning passed for 161 yards and a touchdown and Michael Johnson picked off two passes by the 49ers' J.T. O'Sullivan, who was 16-of-28 passing for 256 yards and touchdown.

Nate Clements returned a blocked field goal attempt 74 yards for a touchdown and Josh Morgan caught five passes for 86 yards and a score for the 49ers.