Hairston hit a two-run homer in the top of the third inning and a solo shot in the sixth.

San Diego also got Adrian Gonzalez's solo homer in the ninth. Five others had one hit for the Padres, winners of back-to-back contests for the first time since June 11-12.

Winner Jake Peavy (6-5) surrendered three hits in seven scoreless innings with two walks and six strikeouts.

After Heath Bell gave up a run, closer Trevor Hoffman recorded his 16th save.

Arizona's runs scored on Orlando Hudson's eighth-inning double and Stephen Drew's ninth-inning homer. Hudson had two of the seven hits in the Diamondbacks' fourth loss in their last five games.

Losing pitcher Doug Davis (3-4) gave up three earned runs and seven hits in eight innings with a walk and seven strikeouts.