Pernice, who shared the second-round lead with Jeff Overton, completed 54 holes at 10-under 200 -- a 54-hole tournament record at this second-year event. K.J. Choi set the mark of 201 in last year's inaugural event.
Steve Stricker is second at 9-under after shooting a 4-under 66 in the third round. Overton had a 71 and slid into a tie for third at 202 along with Tommy Armour III (66) and Nick O'Hern (67).
"I had a lot of chances from 10 to 15 feet today and some of them were above the pins and were tough putts, and you need a few of those to go in to get some momentum," said Pernice, 48. "I'd like to capitalize on my good shots tomorrow and see what happens."