Pernice, who shared the second-round lead with Jeff Overton, completed 54 holes at 10-under 200 -- a 54-hole tournament record at this second-year event. K.J. Choi set the mark of 201 in last year's inaugural event.
Steve Stricker is second at 9-under after shooting a 4-under 66 in the third round. Overton had a 71 and slid into a tie for third at 202 along with Tommy Armour III (66) and Nick O'Hern (67).
"I had a lot of chances from 10 to 15 feet today and some of them were above the pins and were tough putts, and you need a few of those to go in to get some momentum," said Pernice, 48. "I'd like to capitalize on my good shots tomorrow and see what happens."
Swim Week Miami Beach 2014 [PHOTOS]