A 15-4 Wolfpack run left Duke in a 70-57 hole with 12:43 remaining in the game and the Blue Devils still trained 81-73 at the 5:03 mark. But a closing 13-6 spurt gave their long-time coach the milestone win.
Ben McCauley led NCSU with 19 points, three rebounds and three assists.
Javier Gonzalez scored 18 points and Tracy Smith 14 for the Wolfpack (15-14, 4-11), who have dropped seven in a row for the first time since the 2000-01 season.
"A lot of you were here when I started, and at the time, I thought eight victories would have been nice," he told The (Raleigh) News & Observer.
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