Jay Cutler completed 26 of 37 passes for 246 yards and two touchdowns for the Broncos (7-9), who ended the season with a losing record for the first time since 1999.
Tarvaris Jackson threw for 175 yards on 16 of 31 passing with two touchdowns for the Vikings (8-8).
The loss -- Minnesota's second straight -- coupled with Washington's 27-6 win over Dallas Sunday, allowed the Redskins to advance to the NFC playoffs.
Rosie O'Donnell unveils nearly 50-pound weight loss
Justin Bieber crashes Drake Bell's album release party