McNabb completed 24 out of 35 passes for the Eagles (7-8), while Brian Westbrook ran for 100 yards on 17 carries.
Reggie Brown also had one score for Philadelphia.
Drew Brees went 30-of-45 passing for 289 yards and an interception for New Orleans (7-8).
Aaron Stecker had two early touchdown runs in the loss.
Swim Week Miami Beach 2014 [PHOTOS]