Luongo aggravated a rib injury during warm-ups Monday and Sanford was pressed into emergency duty. He lost that game against Los Angeles, but came through Wednesday while his teammates were building a 3-0 lead.
Chris Pronger scored for Anaheim at 5:51 of the second, but Sanford was almost perfect from that point in helping the Canucks defeat the Ducks for the second time this season.
Mathieu Schneider reduced Anaheim's deficit to one with a slap shot that got past Sanford with 1:31 remaining in the game.
Notable deaths of 2014 [PHOTOS]
Michael Sam cut from the Dallas Cowboys