Denver (5-5) had four touchdowns of 40 yards or more in a game for the first time in franchise history and tied San Diego for the AFC West lead.
Brandon Stokley caught three passes for 75 yards, including a 48-yard TD, for the Broncos. Glenn Martinez had an 80-yard punt return for a touchdown, Brandon Marshall added a 41-yard touchdown reception and Andre Hall had a 62-yard TD run.
Vince Young was 26-of-41 for 305 yards with a touchdown and two interceptions for the Titans (6-4), who lost their second straight and fell two games behind Indianapolis in the AFC South. Young added 74 yards on the ground with another touchdown.
Rob Bironas had two field goals for Tennessee.
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