Austin Rogers caught six passes for 62 yards and the game's first touchdown for Tennessee (7-3, 4-2 SEC), which improved to 6-0 at home this season with its third consecutive victory.
Darren McFadden was bottled up for most of the first half, as Arkansas fell into a 27-3 hole. One week after exploding for 323 yards against South Carolina, McFadden finished with 117 yards.
Felix Jones carried the ball only three times for three yards after running for a career-best 174 yards last week.
Casey Dick completed 12-of-22 passes for 140 yards and two interceptions for Arkansas (6-4, 2-4), which saw its three-game winning streak end.