The contest -- played at Wembley Stadium -- was the first NFL game played outside North America. Rainy and cool weather conditions made for a slippery football and neither team was effective on offense.
Manning completed 8-of-22 passes for 59 yards. He scored the Giants' lone touchdown on a scramble when all his receivers were well covered by Miami's secondary.
Miami's Cleo Lemon threw for one touchdown and completed 17-of-30 passes for 149 yards.
Jesse Chatman ran for 79 yards on 16 carries and caught three passes for 21 yards for the winless Dolphins, who have lost 11 in a row dating back to last season.