Pak -- who is seeking to win the event for the fifth time in a decade -- shot a 3-under 68 over the Highland Meadows Golf Club course for a 36-hole total of 131. That tied the tournament record established in 1997 by Kelly Robbins.
Not only has Pak won the tourney four times in the past nine years, she has also finished in the top 10 four other times.
Jin Young Pak, playing in only her fourth event on the LPGA Tour this year, fired a 69 and was alone in second at 6-under 136. Carri Wood (69) and Meg Mallon (65) were at 137 while Morgan Pressel (70) and Jimin Kang (68) were at 138.
"I finished the first two rounds by putting up a good score," Se Ri Pak said. "I did not make as many putts as yesterday, but I'm really happy about it."
Cristie Kerr (70), playing for the first time since capturing the U.S. Women's Open, was tied with six players for seventh at 139.